MeSH Browser

MeSH Heading: E-Box Elements
Tree Number(s): G02.111.570.080.689.330.240; G05.360.080.689.330.240; G05.360.340.024.340.137.750.249.240
Unique ID: D024721
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D024721
Scope Note: DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
Entry Term(s): E-Box Motifs; E-Box Sequences; E-Box Sites
Public MeSH Note: 2002
History Note: 2002
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2009/07/14

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0371558
Scope Note: DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
Terms: E-Box Elements Preferred Term
Term UI T427233
Date10/26/2000
LexicalTag ABX
ThesaurusID NLM (2002); E-Box Motifs
Term UI T427236
Date10/26/2000
LexicalTag ABX
ThesaurusID NLM (2002); E-Box Sequences
Term UI T427235
Date10/26/2000
LexicalTag ABX
ThesaurusID NLM (2002); E-Box Sites
Term UI T427234
Date10/26/2000
LexicalTag ABX
ThesaurusID NLM (2002)

E-Box Elements MeSH Descriptor Data 2025