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Phosphofructokinase-1, Muscle Type MeSH Descriptor Data 2023


MeSH Heading
Phosphofructokinase-1, Muscle Type
Tree Number(s)
D08.811.913.696.620.225.850.500.500
Unique ID
D025203
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D025203
Scope Note
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In humans, PHOSPHOFRUCTOKINASE-1 in muscle exists as the homotetramer of M subunits. Defects in this muscle enzyme cause GLYCOGEN STORAGE DISEASE TYPE VII, also known as Tarui's disease.
Entry Term(s)
6-Phosphofructokinase, Muscle Type
Phosphofructo-1-kinase Isozyme A
Registry Number
EC 2.7.1.-
Previous Indexing
6-Phosphofructokinase (1977-2001)
Public MeSH Note
2002
History Note
2002
Entry Combination
deficiency:Glycogen Storage Disease Type VII
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2005/07/25
Phosphofructokinase-1, Muscle Type Preferred
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