MeSH Browser

MeSH Heading: Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent
Tree Number(s): D08.811.682.047.820.150.415.250
Unique ID: D025781
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D025781
Annotation: do not confuse with HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT
Scope Note: Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.
Entry Term(s): 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent; HMG CoA Reductase, NAD-Dependent; HMG CoA Reductases, NAD-Dependent; Hydroxymethylglutaryl CoA Reductase, NAD-Dependent
Registry Numbers: EC 1.1.1.88
Previous Indexing: Hydroxymethylglutaryl CoA Reductases (1989-2001)
Public MeSH Note: 2002
History Note: 2002
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2013/07/08

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Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent MeSH Descriptor Data 2024