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Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent MeSH Descriptor Data 2023


MeSH Heading
Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent
Tree Number(s)
D08.811.682.047.820.150.415.250
Unique ID
D025781
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D025781
Annotation
do not confuse with HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT
Scope Note
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.
Entry Term(s)
3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent
HMG CoA Reductase, NAD-Dependent
HMG CoA Reductases, NAD-Dependent
Hydroxymethylglutaryl CoA Reductase, NAD-Dependent
Registry Number
EC 1.1.1.88
Previous Indexing
Hydroxymethylglutaryl CoA Reductases (1989-2001)
Public MeSH Note
2002
History Note
2002
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2013/07/08
Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent Preferred
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