NLM Logo

Fusion Regulatory Protein-1 MeSH Descriptor Data 2025


MeSH Heading
Fusion Regulatory Protein-1
Tree Number(s)
D12.776.157.530.200.374.750.500
D12.776.157.530.200.500.500.500
D12.776.157.530.937.313.500
D12.776.543.585.200.374.750.500
D12.776.543.585.200.500.500.500
D12.776.543.585.937.313.500
Unique ID
D027261
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D027261
Scope Note
A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (FUSION REGULATORY PROTEIN 1, HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (FUSION REGULATORY PROTEIN 1, LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.
Entry Term(s)
4F2 Antigen
4F2-antigen
Antigen 4F2
Antigens, CD98
CD98 Antigen
CD98 Antigens
CD98 Transport Proteins
FRP-1 protein
H4F2 Antigen
Human 4F2 Antigen
Human 4F2 Cell-Surface Antigen
Human Lymphocyte Activation Antigen 4F2
Previous Indexing
Antigens, CD (1996-2001)
Antigens, Surface (1989-1995)
Carrier Proteins (1996-2001)
Public MeSH Note
2018; see ANTIGENS, CD98 1988-2017; FUSION REGULATORY PROTEIN-1 was indexed under CARRIER PROTEINS 1996-2001; under ANTIGENS CD 1996-2001; and under ANTIGENS, SURFACE 1989-1995
History Note
2018 (1988)
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2017/05/24
Fusion Regulatory Protein-1 Preferred
Human 4F2 Antigen Narrower
page delivered in 0.186s