MeSH Browser

MeSH Heading: Long-Term Synaptic Depression
Tree Number(s): G11.561.638.355
Unique ID: D036881
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D036881
Annotation: note category: do not confuse with clinical DEPRESSION or DEPRESSIVE DISORDERS
Scope Note: A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
Entry Term(s): Depotentiation; Homosynaptic Depression; Long-Term Depression, Neurophysiologic; Long-Term Depression, Neurophysiological; Long-Term Depression, Physiologic; Long-Term Depression, Physiological
NLM Classification #: WL 102
Previous Indexing: Neuronal Plasticity (1985-2002)
Public MeSH Note: 2008; see LONG-TERM DEPRESSION (PHYSIOLOGY) 2003-2007
History Note: 2008 (2003)
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2016/06/23

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0411349
Scope Note: A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY.
Terms: Long-Term Synaptic Depression Preferred Term
Term UI T492102
Date05/02/2002
LexicalTag NON
ThesaurusID NLM (2003); Long-Term Depression, Physiologic
Term UI T677695
Date07/11/2006
LexicalTag NON
ThesaurusID NLM (2008); Long-Term Depression, Neurophysiologic
Term UI T677696
Date07/11/2006
LexicalTag NON
ThesaurusID NLM (2008); Long-Term Depression, Neurophysiological
Term UI T682830
Date10/04/2006
LexicalTag NON
ThesaurusID NLM (2008); Long-Term Depression, Physiological
Term UI T682831
Date10/04/2006
LexicalTag NON
ThesaurusID NLM (2008)

Long-Term Synaptic Depression MeSH Descriptor Data 2025