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Mineralocorticoid Excess Syndrome, Apparent
MeSH Descriptor Data 2023
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Mineralocorticoid Excess Syndrome, Apparent
Tree Number(s)
C16.320.565.925.500
C18.452.648.925.500
Unique ID
D043204
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D043204
Scope Note
A hereditary disease characterized by childhood onset
HYPERTENSION
, hypokalemic alkalosis, and low
RENIN
and
ALDOSTERONE
secretion. It results from a defect in the activity of the
11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2
enzyme which results in inadequate conversion of
CORTISOL
to
CORTISONE
. The build up of unprocessed cortisol to levels that stimulate
MINERALOCORTICOID RECEPTORS
creates the appearance of having excessive
MINERALOCORTICOIDS
.
Entry Term(s)
Apparent Mineralocorticoid Excess Syndrome
Previous Indexing
Metabolism, Inborn Errors (1977-2003)
Public MeSH Note
2004
History Note
2004
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2006/07/05
Allowable Qualifiers
blood (BL)
cerebrospinal fluid (CF)
chemically induced (CI)
classification (CL)
complications (CO)
diagnosis (DI)
diagnostic imaging (DG)
diet therapy (DH)
drug therapy (DT)
economics (EC)
embryology (EM)
enzymology (EN)
epidemiology (EP)
ethnology (EH)
etiology (ET)
genetics (GE)
history (HI)
immunology (IM)
metabolism (ME)
microbiology (MI)
mortality (MO)
nursing (NU)
parasitology (PS)
pathology (PA)
physiopathology (PP)
prevention & control (PC)
psychology (PX)
radiotherapy (RT)
rehabilitation (RH)
surgery (SU)
therapy (TH)
urine (UR)
veterinary (VE)
virology (VI)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Metabolism, Inborn Errors [C16.320.565]
Steroid Metabolism, Inborn Errors [C16.320.565.925]
Adrenal Hyperplasia, Congenital [C16.320.565.925.249]
Antley-Bixler Syndrome Phenotype [C16.320.565.925.324]
Ichthyosis, X-Linked [C16.320.565.925.400]
Mineralocorticoid Excess Syndrome, Apparent [C16.320.565.925.500]
Smith-Lemli-Opitz Syndrome [C16.320.565.925.875]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Metabolism, Inborn Errors [C18.452.648]
Steroid Metabolism, Inborn Errors [C18.452.648.925]
Adrenal Hyperplasia, Congenital [C18.452.648.925.249]
Antley-Bixler Syndrome Phenotype [C18.452.648.925.324]
Ichthyosis, X-Linked [C18.452.648.925.400]
Mineralocorticoid Excess Syndrome, Apparent [C18.452.648.925.500]
Smith-Lemli-Opitz Syndrome [C18.452.648.925.875]
Expand All
Collapse All
Mineralocorticoid Excess Syndrome, Apparent
Preferred
Concept UI
M0442605
Scope Note
A hereditary disease characterized by childhood onset
HYPERTENSION
, hypokalemic alkalosis, and low
RENIN
and
ALDOSTERONE
secretion. It results from a defect in the activity of the
11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2
enzyme which results in inadequate conversion of
CORTISOL
to
CORTISONE
. The build up of unprocessed cortisol to levels that stimulate
MINERALOCORTICOID RECEPTORS
creates the appearance of having excessive
MINERALOCORTICOIDS
.
Terms
Mineralocorticoid Excess Syndrome, Apparent
Preferred Term
Term UI
T533450
Date
02/24/2003
LexicalTag
NON
ThesaurusID
NLM (2004)
Apparent Mineralocorticoid Excess Syndrome
Term UI
T526967
Date
11/25/2002
LexicalTag
NON
ThesaurusID
NLM (2004)
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