MeSH Browser

MeSH Heading: Mineralocorticoid Excess Syndrome, Apparent
Tree Number(s): C16.320.565.925.500; C18.452.648.925.500
Unique ID: D043204
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D043204
Scope Note: A hereditary disease characterized by childhood onset HYPERTENSION, hypokalemic alkalosis, and low RENIN and ALDOSTERONE secretion. It results from a defect in the activity of the 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 enzyme which results in inadequate conversion of CORTISOL to CORTISONE. The build up of unprocessed cortisol to levels that stimulate MINERALOCORTICOID RECEPTORS creates the appearance of having excessive MINERALOCORTICOIDS.
Entry Term(s): Apparent Mineralocorticoid Excess Syndrome
Previous Indexing: Metabolism, Inborn Errors (1977-2003)
Public MeSH Note: 2004
History Note: 2004
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2006/07/05

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

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psychology (PX)

radiotherapy (RT)

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surgery (SU)

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urine (UR)

veterinary (VE)

virology (VI)

Mineralocorticoid Excess Syndrome, Apparent MeSH Descriptor Data 2022