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Mineralocorticoid Excess Syndrome, Apparent MeSH Descriptor Data 2023


MeSH Heading
Mineralocorticoid Excess Syndrome, Apparent
Tree Number(s)
C16.320.565.925.500
C18.452.648.925.500
Unique ID
D043204
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D043204
Scope Note
A hereditary disease characterized by childhood onset HYPERTENSION, hypokalemic alkalosis, and low RENIN and ALDOSTERONE secretion. It results from a defect in the activity of the 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 2 enzyme which results in inadequate conversion of CORTISOL to CORTISONE. The build up of unprocessed cortisol to levels that stimulate MINERALOCORTICOID RECEPTORS creates the appearance of having excessive MINERALOCORTICOIDS.
Entry Term(s)
Apparent Mineralocorticoid Excess Syndrome
Previous Indexing
Metabolism, Inborn Errors (1977-2003)
Public MeSH Note
2004
History Note
2004
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2006/07/05
Mineralocorticoid Excess Syndrome, Apparent Preferred
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