MeSH Browser

MeSH Heading: Matrix Attachment Regions
Tree Number(s): G02.111.570.080.534; G05.360.080.534
Unique ID: D045170
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D045170
Scope Note: Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.
Entry Term(s): MAR Elements; MAR-SAR Recognition Signature Sequence; MRS Sequence; Matrix-Attached Regions; SAR Elements; Scaffold Attachment Regions; Scaffold-Attached Regions
Previous Indexing: Nuclear Matrix/metabolism (1990-2003)
Public MeSH Note: 2004
History Note: 2004
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2011/12/12

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

physiology (PH)

radiation effects (RE)

Concept UI: M0447380
Scope Note: Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.
Terms: Matrix Attachment Regions Preferred Term
Term UI T538967
Date04/22/2003
LexicalTag NON
ThesaurusID NLM (2004); MAR Elements
Term UI T538968
Date04/22/2003
LexicalTag NON
ThesaurusID NLM (2004); Matrix-Attached Regions
Term UI T539049
Date04/23/2003
LexicalTag NON
ThesaurusID NLM (2004); SAR Elements
Term UI T536440
Date03/24/2003
LexicalTag NON
ThesaurusID NLM (2004); Scaffold Attachment Regions
Term UI T536439
Date03/24/2003
LexicalTag NON
ThesaurusID NLM (2004); Scaffold-Attached Regions
Term UI T539050
Date04/23/2003
LexicalTag NON
ThesaurusID NLM (2004)

Matrix Attachment Regions MeSH Descriptor Data 2025