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Laron Syndrome MeSH Descriptor Data 2023


MeSH Heading
Laron Syndrome
Tree Number(s)
C05.116.099.343.679
C16.320.240.750
C19.297.656
Unique ID
D046150
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D046150
Scope Note
An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.
Entry Term(s)
Growth Hormone Insensitivity Syndrome
Growth Hormone Receptor Defect
Growth Hormone Receptor Deficiency
Laron Dwarfism
Laron Type Dwarfism I
Pituitary Dwarfism II
Primary GH Resistance
Primary Growth Hormone Resistance
Severe GH Insensitivity
NLM Classification #
WK 550
Previous Indexing
Dwarfism (1976-2004)
Growth Hormone (1976-2004)
Receptors, Cell Surface (1976-2004)
Receptors, Somatotropin (1991-2004)
Public MeSH Note
2005
History Note
2005
Date Established
2005/01/01
Date of Entry
2004/07/07
Revision Date
2012/07/03
Laron Syndrome Preferred
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