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Core Binding Factor Alpha 2 Subunit MeSH Descriptor Data 2023


MeSH Heading
Core Binding Factor Alpha 2 Subunit
Tree Number(s)
D12.776.930.155.200.200
Unique ID
D050676
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050676
Scope Note
A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.
Entry Term(s)
AML1A Protein
AML1B Protein
AML1C Protein
AML1D Protein
Acute Myeloid Leukemia 1 Protein
Acute Myeloid Leukemia 1A Protein
Acute Myeloid Leukemia 1B Protein
Acute Myeloid Leukemia 1C Protein
Acute Myeloid Leukemia 1D Protein
Core-Binding Factor Alpha 2 Protein
Pebp2a2 Protein
Runt-Related Transcription Factor 1
Runx1 Protein
Registry Number
0
Previous Indexing
DNA-Binding Proteins (1996-2005)
Neoplasm Proteins (1993-1996)
Proto-Oncogene Proteins (1996-2005)
Transcription Factors (1996-2005)
Public MeSH Note
2006; RUNX1 PROTEIN was indexed under DNA-BINDING PROTEINS 1996-2005, NEOPLASM PROTEINS 1993-1996, PROTO-ONCOGENE PROTEINS 1996-2005, & TRANSCRIPTION FACTORS 1996-2005
History Note
2006(1993)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2017/06/02
Core Binding Factor Alpha 2 Subunit Preferred
Acute Myeloid Leukemia 1D Protein Narrower
Acute Myeloid Leukemia 1C Protein Narrower
Acute Myeloid Leukemia 1B Protein Narrower
Acute Myeloid Leukemia 1A Protein Narrower
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