MeSH Browser

MeSH Heading: Leucine Dehydrogenase
Tree Number(s): D08.811.682.664.500.724
Unique ID: D050803
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050803
Scope Note: An octameric enzyme belonging to the superfamily of amino acid dehydrogenases. Leucine dehydrogenase catalyzes the reversible oxidative deamination of L-LEUCINE, to 4-methyl-2-oxopentanoate (2-ketoisocaproate) and AMMONIA, with the corresponding reduction of the cofactor NAD+.
Entry Term(s): L-Leucine Dehydrogenase; Leucine (Branched-Chain Amino Acid) Dehydrogenase
Related Numbers: 9082-71-7
Previous Indexing: Amino Acid Oxidoreductases (1970-2005); Leucine (1970-1979)
Public MeSH Note: 2006; LEUCINE DEHYDROGENASE was indexed under AMINO ACID OXIDOREDUCTASES 1970-2005 & LEUCINE 1970-1982
History Note: 2006(1970)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0076542
Related Numbers: 9082-71-7
Scope Note: An octameric enzyme belonging to the superfamily of amino acid dehydrogenases. Leucine dehydrogenase catalyzes the reversible oxidative deamination of L-LEUCINE, to 4-methyl-2-oxopentanoate (2-ketoisocaproate) and AMMONIA, with the corresponding reduction of the cofactor NAD+.
Terms: Leucine Dehydrogenase Preferred Term
Term UI T106545
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); L-Leucine Dehydrogenase
Term UI T624514
Date12/16/2004
LexicalTag NON
ThesaurusID NLM (2006); Leucine (Branched-Chain Amino Acid) Dehydrogenase
Term UI T106544
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Leucine Dehydrogenase MeSH Descriptor Data 2025