MeSH Browser

MeSH Heading: Cyclooxygenase 2
Tree Number(s): D08.811.600.720.750
Unique ID: D051546
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051546
Scope Note: An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Entry Term(s): COX-2 Prostaglandin Synthase; Cyclo-Oxygenase II; Cyclooxygenase-2; PGHS-2; PTGS2; Prostaglandin H Synthase-2
Registry Numbers: EC 1.14.99.1
Public MeSH Note: 2006; CYCLOOXYGENASE 2 was indexed under ISOENZYMES, under PEROXIDASES & PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 1996-2005
History Note: 2006(1996)
Entry Combination: antagonists & inhibitors:Cyclooxygenase 2 Inhibitors
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 1955/01/01

Entry Combination: antagonists & inhibitors:Cyclooxygenase 2 Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0258705
Registry Numbers: EC 1.14.99.1
Scope Note: An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Terms: Cyclooxygenase 2 Preferred Term
Term UI T288710
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); PGHS-2
Term UI T288706
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2006); Prostaglandin H Synthase-2
Term UI T403545
Date12/22/1999
LexicalTag NON
ThesaurusID NLM (2006); Cyclooxygenase-2
Term UI T288709
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); COX-2 Prostaglandin Synthase
Term UI T638652
Date04/29/2005
LexicalTag ABX
ThesaurusID NLM (2006); Cyclo-Oxygenase II
Term UI T288708
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); PTGS2
Term UI T288707
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2006)

Cyclooxygenase 2 MeSH Descriptor Data 2024