MeSH Browser

MeSH Heading: Phospholipase C gamma
Tree Number(s): D08.811.277.352.640.700.700.562.750; D12.776.476.557.750
Unique ID: D051966
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051966
Scope Note: A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains located between two halves of the CATALYTIC DOMAIN.
Entry Term(s): PLC gamma1; PLC-gamma; PLC-gamma 2; PLC-gamma D; PLCgamma2; Phospholipase C gamma 1; Phospholipase C gamma 2; Phospholipase C gamma D; Phospholipase C gamma1; Phospholipase C gamma2; Phospholipase C gammaD
Related Numbers: EC 3.1.4.3
Public MeSH Note: 2006; PHOSPHOLIPASE C GAMMA was indexed under PHOSPHOLIPASE C 1994-2005
History Note: 2006(1994)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0225969
Terms: Phospholipase C gamma 2 Preferred Term
Term UI T634180
Date03/23/2005
LexicalTag NON
ThesaurusID NLM (2006); PLCgamma2
Term UI T255971
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); Phospholipase C gamma2
Term UI T255974
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); PLC-gamma 2
Term UI T634181
Date03/23/2005
LexicalTag ABX
ThesaurusID NLM (2006)

Phospholipase C gamma MeSH Descriptor Data 2025