MeSH Browser

MeSH Heading: Alpha-Amanitin
Tree Number(s): D04.345.566.050.111; D12.644.456.050.111; D12.644.641.050.111; D23.946.587.175.111
Unique ID: D053959
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053959
Scope Note: A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POLYMERASE II. Poisoning may require LIVER TRANSPLANTATION.
Entry Term(s): Alpha-Amanitine
Pharm Action: Poisons
Nucleic Acid Synthesis Inhibitors
Registry Numbers: 0
Previous Indexing: Amanitins (1980-2007)
See Also: Mushroom Poisoning
Public MeSH Note: 2008; see AMANITINS 1980-2007
History Note: 2008; use AMANITINS 1980-2007
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2018/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Alpha-Amanitin MeSH Descriptor Data 2024