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Leukemia, Large Granular Lymphocytic MeSH Descriptor Data 2023

MeSH Heading
Leukemia, Large Granular Lymphocytic
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.
Entry Term(s)
Aggressive NK Cell Leukemia
Aggressive Natural Killer Cell Leukemia
LGL Leukemia
Large Granular Lymphocyte Leukemia
Large Granular Lymphocytosis
Leukemia, LGL
Leukemia, Lymphocytic, Large Granular
Leukemia, NK-LGL
Leukemia, Natural Killer Cell Large Granular Lymphocytic
Leukemia, T-Cell Large Granular Lymphocytic
Leukemia, T-LGL
Lymphoproliferative Disease of Granular Lymphocytes
Lymphoproliferative Disease of Large Granular Lymphocytes
NK-Cell Large Granular Lymphocytic Leukemia
NK-LGL Leukemia
Natural Killer Cell Large Granular Lymphocytic Leukemia
T-Cell Large Granular Lymphocyte Leukemia
T-Cell Large Granular Lymphocytic Leukemia
T-LGL Leukemia
Previous Indexing
Leukemia, Lymphocytic (1987-2007)
See Also
Public MeSH Note
2008; see LEUKEMIA, LYMPHOCYTIC 1997-2007
History Note
2008; use LEUKEMIA, LYMPHOCYTIC 1997-2007
Date Established
Date of Entry
Revision Date
Leukemia, Large Granular Lymphocytic Preferred
Leukemia, T-Cell Large Granular Lymphocytic Narrower
Leukemia, Natural Killer Cell Large Granular Lymphocytic Narrower
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