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Receptors, KIR MeSH Descriptor Data 2022


MeSH Heading
Receptors, KIR
Tree Number(s)
D12.776.543.750.705.895.500
Unique ID
D054340
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054340
Annotation
general; prefer specifics
Scope Note
A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.
Entry Term(s)
KIR Family Receptors
KIR Receptor
KIR Receptors
Killer Cell Immunoglobulin-Like Receptor
Killer Cell Immunoglobulin-Like Receptors
Killer Immunoglobulin-Like Receptor
Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors
Killer Inhibitory Receptor
Killer Inhibitory Receptors
Receptor, Killer Inhibitory
Receptor, p58 NK Cell
p58 NK Cell Inhibitory Receptor
p58 NK Cell Receptor
p58 NK Cell Receptors
p58 Natural Killer Cell Receptor
Registry Number
0
Public MeSH Note
2008; KIR RECEPTORS (now RECEPTORS, KIR) was indexed under RECEPTORS, IMMUNOLOGIC 1997-2007
History Note
2008(1997)
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
2008/07/08
Receptors, KIR Preferred
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