MeSH Browser

MeSH Heading: Phospholipases A2, Secretory
Tree Number(s): D08.811.277.352.100.680.750.937.750
Unique ID: D054497
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054497
Annotation: /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
Scope Note: A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes.
Entry Term(s): Phospholipases A2, Secreted; SPLA2 Phospholipases; Secreted Phospholipase A2; Secreted Phospholipases A2; Secretory Phospholipase A2; sPLA(2); sPLA2; sPLA2s
Previous Indexing: Phospholipases A (1980-2007)
Public MeSH Note: 2008; SECRETORY PHOSPHOLIPASE A2 was indexed under PHOSPHOLIPASES A 1998-2007
History Note: 2008
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2020/06/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0505572
Scope Note: A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes.
Terms: Phospholipases A2, Secretory Preferred Term
Term UI T689779
Date01/23/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipases A2, Secreted
Term UI T689424
Date01/17/2007
LexicalTag NON
ThesaurusID NLM (2008); Secreted Phospholipase A2
Term UI T001083380
Date06/23/2020
LexicalTag NON
ThesaurusID NLM (2021); Secreted Phospholipases A2
Term UI T689425
Date01/17/2007
LexicalTag NON
ThesaurusID NLM (2008); Secretory Phospholipase A2
Term UI T639522
Date05/04/2005
LexicalTag NON
ThesaurusID NLM (2008); sPLA(2)
Term UI T316230
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (2008); SPLA2 Phospholipases
Term UI T689426
Date01/17/2007
LexicalTag ABX
ThesaurusID NLM (2008); sPLA2
Term UI T001083379
Date06/23/2020
LexicalTag NON
ThesaurusID NLM (2021); sPLA2s
Term UI T689741
Date01/22/2007
LexicalTag ABB
ThesaurusID NLM (2008)

Phospholipases A2, Secretory MeSH Descriptor Data 2025