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Acid Ceramidase MeSH Descriptor Data 2023


MeSH Heading
Acid Ceramidase
Tree Number(s)
D08.811.277.087.250.100
Unique ID
D055573
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D055573
Scope Note
A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
Registry Number
EC 3.5.1.23
Previous Indexing
Galactosylgalactosylglucosylceramidase (1974-2008)
Public MeSH Note
2009; see CERAMIDE TRIHEXOSIDASE 1983-2008
History Note
2009(1982); use GALACTOSYLGALACTOSYLGLUCOSYLCERAMIDASE 1983-2008
Entry Combination
deficiency:Farber Lipogranulomatosis
Date Established
2009/01/01
Date of Entry
2008/07/08
Acid Ceramidase Preferred
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