A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.
Entry Term(s)
Chromatin Assembly Complex-1
Chromatin Assembly Complex-1, p150 Subunit
Chromatin Assembly Complex-1, p60 Subunit
Registry Number
0
Public MeSH Note
2010; CHROMATIN ASSEMBLY FACTOR-1 was indexed under CHROMOSOMAL PROTEINS, NON-HISTONE and DNA-BINDING PROTEINS 1995-2009
A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.
