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Iridocorneal Endothelial Syndrome MeSH Descriptor Data 2026


MeSH Heading
Iridocorneal Endothelial Syndrome
Tree Number(s)
C11.204.497
C11.941.375.322
Unique ID
D057129
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D057129
Scope Note
A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.
Entry Term(s)
Chandler Syndrome
Chandler's Syndrome
ICE Syndrome
Iris Atrophy with Corneal Edema and Glaucoma
Previous Indexing
Corneal Diseases (1979-2009)
Iris Diseases (1979-2009)
See Also
Glaucoma
Public MeSH Note
2010
History Note
2010
Date Introduced
2010/01/01
Last Updated
2020/02/28
Iridocorneal Endothelial Syndrome Preferred
Chandler Syndrome Narrower
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