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Central Tolerance MeSH Descriptor Data 2023


MeSH Heading
Central Tolerance
Tree Number(s)
G12.535.425.800.200
Unique ID
D061167
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D061167
Scope Note
The mechanism, in central lymphoid organs (THYMUS; BONE MARROW), that prevents immature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished by CLONAL ANERGY and CLONAL DELETION.
Previous Indexing
Immune Tolerance (1980-2011)
Self Tolerance (1998-2011)
Public MeSH Note
2012
History Note
2012
Date Established
2012/01/01
Date of Entry
2011/06/24
Revision Date
2016/06/16
Central Tolerance Preferred
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