MeSH Browser

MeSH Heading: Claudin-5
Tree Number(s): D12.776.543.940.200.500
Unique ID: D062507
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D062507
Scope Note: A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
Entry Term(s): Claudin 5; TMVCF Protein; Transmembrane Protein Deleted in Velocardiofacial Syndrome
Previous Indexing: Claudins (2011-2012); Membrane Proteins (1997-2010)
See Also: DiGeorge Syndrome
Public MeSH Note: 2013
History Note: 2013
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/01/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0568519
Scope Note: A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
Terms: Claudin-5 Preferred Term
Term UI T813222
Date11/25/2011
LexicalTag NON
ThesaurusID NLM (2013); Claudin 5
Term UI T813223
Date11/25/2011
LexicalTag NON
ThesaurusID NLM (2013); Transmembrane Protein Deleted in Velocardiofacial Syndrome
Term UI T813224
Date11/25/2011
LexicalTag NON
ThesaurusID NLM (2013); TMVCF Protein
Term UI T813225
Date11/25/2011
LexicalTag ABX
ThesaurusID NLM (2013)

Claudin-5 MeSH Descriptor Data 2025