MeSH Browser

MeSH Heading: Hydroxymethylglutaryl CoA Reductases
Tree Number(s): D08.811.682.047.820.150.415
Unique ID: D006903
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006903
Scope Note: Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
Entry Term(s): 3-Hydroxy-3-methylglutaryl CoA Reductase; HMG CoA Reductase; HMG CoA Reductases; Hydroxymethylglutaryl CoA Reductase
Registry Numbers: EC 1.1.1.-
NLM Classification #: QU 140
Previous Indexing: Alcohol Oxidoreductases (1966-1977); Glutarates (1966-1974); Mevalonic Acid (1966-1974)
See Also: Hydroxymethylglutaryl-CoA Reductase Inhibitors
Public MeSH Note: 78; was see under ALCOHOL OXIDOREDUCTASES 1975-77
History Note: 78(75); was see under ALCOHOL OXIDOREDUCTASES 1975-77
Entry Combination: antagonists & inhibitors:Hydroxymethylglutaryl-CoA Reductase Inhibitors
Date Established: 1978/01/01
Date of Entry: 1974/11/11
Revision Date: 2013/07/08

Entry Combination: antagonists & inhibitors:Hydroxymethylglutaryl-CoA Reductase Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0010772
Registry Numbers: EC 1.1.1.-
Scope Note: Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
Terms: Hydroxymethylglutaryl CoA Reductases Preferred Term
Term UI T020784
Date01/01/1999
LexicalTag ABX
ThesaurusID NLM (1975); 3-Hydroxy-3-methylglutaryl CoA Reductase
Term UI T020785
Date01/16/1990
LexicalTag NON
ThesaurusID NLM (1991); HMG CoA Reductase
Term UI T020782
Date12/18/1981
LexicalTag NON
ThesaurusID UNK (19XX); HMG CoA Reductases
Term UI T020783
Date03/23/1987
LexicalTag NON
ThesaurusID UNK (19XX); Hydroxymethylglutaryl CoA Reductase
Term UI T432545
Date01/08/2001
LexicalTag NON
ThesaurusID NLM (2002)

Hydroxymethylglutaryl CoA Reductases MeSH Descriptor Data 2024