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balsalazide MeSH Supplementary Concept Data 2021


MeSH Supplementary
balsalazide
Unique ID
C038637
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C038637
Entry Term(s)
5-(carboxyethylcarbamoyl-4-phenylazo)salicylic acid
BX 661A
BX661A
Colazal
Colazide
balsalazide disodium
balsalazine
Pharm Action
Anti-Inflammatory Agents, Non-Steroidal
Gastrointestinal Agents
Registry Number
P80AL8J7ZP
Related Numbers
82101-18-6
CAS Type 1 Name
Benzoic acid, 5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxy-, disodium salt
Previous Indexing
*AMINOSALICYLIC ACIDS (1983-2006)
Heading Mapped to
*Phenylhydrazines
*Mesalamine
Frequency
83
Note
a mesalamine 5-aminosalicylate prodrug; 99% of ingested drug remains intact through the stomach and is delivered to and activated in the colon; used for inflammatory bowel disease, ulcerative colitis and radiation-induced proctosigmoiditis but avoided in patients with known hypersensitivity reaction to salicylates or mesalamine; structure in first source
Source
Dig Dis Sci 1983;28(7):609
Indexing Information
Colitis, Ulcerative
Prodrugs
Inflammatory Bowel Diseases
Date of Entry
1983/08/11
Revision Date
2014/10/22
balsalazide Preferred
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