MeSH Browser

MeSH Heading: Prodrugs
Tree Number(s): D26.675
Unique ID: D011355
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D011355
Annotation: coordinate with specific drug
Scope Note: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Entry Term(s): Drug Precursor; Drug Precursors; Pro-Drug; Pro-Drugs; Prodrug
NLM Classification #: QV 785
Previous Indexing: Delayed-Action Preparations (1966-1987)
Public MeSH Note: 89; was see under DRUGS 1988
History Note: 89(88); was see under DRUGS 1988
Date Established: 1989/01/01
Date of Entry: 1987/05/04
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

Concept UI: M0017642
Scope Note: A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
Terms: Prodrugs Preferred Term
Term UI T033488
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1988); Pro-Drug
Term UI T000997678
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Drug Precursor
Term UI T000997679
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Prodrug
Term UI T000996209
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Drug Precursors
Term UI T033487
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX); Pro-Drugs
Term UI T033489
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Prodrugs MeSH Descriptor Data 2025