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ProTides MeSH Descriptor Data 2025


MeSH Heading
ProTides
Tree Number(s)
D13.695.623
D26.675.500
Unique ID
D000095802
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000095802
Scope Note
A class of prodrugs consisting of a 5'-nucleoside monophosphate in which the two hydroxyl groups are masked with an amino acid ester and an aryloxy component which once in the cell is enzymatically metabolized to deliver free 5'-monophosphate, and further transformed to the active 5'-triphosphate form of the nucleoside analogue.
Entry Term(s)
Pro-Tide
Pro-Tides
ProTide
Prodrug Nucleotide
Prodrug Nucleotides
Public MeSH Note
2024
History Note
2024
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/06/02
ProTides Preferred
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