Serotonin and Noradrenaline Reuptake Inhibitors MeSH Descriptor Data 2025

MeSH Heading: Serotonin and Noradrenaline Reuptake Inhibitors
Tree Number(s): D27.505.519.562.437.693; D27.505.519.625.600.693; D27.505.696.577.600.693
Unique ID: D000068760
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000068760
Scope Note: Drugs that selectively block or suppress the plasma membrane transport of SEROTONIN and NORADRENALINE into axon terminals and are used as ANTIDEPRESSIVE AGENTS.
Entry Term(s): SNRI; SNRIs; SSRIs and NRIs; Serotonin and Noradrenaline Uptake Inhibitors; Serotonin and Norepinephrine Reuptake Inhibitors; Serotonin and Norepinephrine Uptake Inhibitors
Previous Indexing: Adrenergic Uptake Inhibitors (1999-2015); Serotonin Uptake Inhibitors (1999-2015)
Public MeSH Note: 2016
History Note: 2016
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Molecular Mechanisms of Pharmacological Action [D27.505.519]
    - Membrane Transport Modulators [D27.505.519.562]
      - Neurotransmitter Uptake Inhibitors [D27.505.519.562.437]
        
        Adrenergic Uptake Inhibitors [D27.505.519.562.437.050]
        
        Dopamine Uptake Inhibitors [D27.505.519.562.437.220]
        
        GABA Uptake Inhibitors [D27.505.519.562.437.535]
        
        Serotonin and Noradrenaline Reuptake Inhibitors [D27.505.519.562.437.693]
        
        Selective Serotonin Reuptake Inhibitors [D27.505.519.562.437.850]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Molecular Mechanisms of Pharmacological Action [D27.505.519]
    - Neurotransmitter Agents [D27.505.519.625]
      - Neurotransmitter Uptake Inhibitors [D27.505.519.625.600]
        
        Adrenergic Uptake Inhibitors [D27.505.519.625.600.050]
        
        Dopamine Uptake Inhibitors [D27.505.519.625.600.220]
        
        GABA Uptake Inhibitors [D27.505.519.625.600.535]
        
        Serotonin and Noradrenaline Reuptake Inhibitors [D27.505.519.625.600.693]
        
        Selective Serotonin Reuptake Inhibitors [D27.505.519.625.600.850]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Physiological Effects of Drugs [D27.505.696]
    - Neurotransmitter Agents [D27.505.696.577]
      - Neurotransmitter Uptake Inhibitors [D27.505.696.577.600]
        
        Adrenergic Uptake Inhibitors [D27.505.696.577.600.050]
        
        Dopamine Uptake Inhibitors [D27.505.696.577.600.220]
        
        GABA Uptake Inhibitors [D27.505.696.577.600.535]
        
        Serotonin and Noradrenaline Reuptake Inhibitors [D27.505.696.577.600.693]
        
        Selective Serotonin Reuptake Inhibitors [D27.505.696.577.600.850]

Serotonin and Noradrenaline Reuptake Inhibitors Preferred

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