MeSH Browser

MeSH Heading: Antidepressive Agents
Tree Number(s): D27.505.954.427.700.122
Unique ID: D000928
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000928
Annotation: general or unspecified; prefer specific groups
Scope Note: Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Entry Term(s): Antidepressant; Antidepressant Drug; Antidepressant Drugs; Antidepressant Medication; Antidepressants; Antidepressive Agent; Thymoanaleptic; Thymoanaleptics; Thymoleptic; Thymoleptics
Registry Numbers: 0
NLM Classification #: QV 77.5
See Also: Monoamine Oxidase Inhibitors
Public MeSH Note: 66; PSYCHIC ENERGIZERS was see ANTIDEPRESSIVE AGENTS 1963-94; THYMOLEPTICS was see TRANQUILIZING AGENTS 1969-78
Online Note: use ANTIDEPRESSIVE AGENTS to search PSYCHIC ENERGIZERS 1966-94; use ANTIDEPRESSIVE AGENTS & TRANQUILIZING AGENTS to search THYMOLEPTICS 1969-78
History Note: 66; PSYCHIC ENERGIZERS was see ANTIDEPRESSIVE AGENTS 1963-94; THYMOLEPTICS was see TRANQUILIZING AGENTS 1969-78
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2021/03/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Central Nervous System Agents [D27.505.954.427]
      - Psychotropic Drugs [D27.505.954.427.700]
        
        Antidepressive Agents [D27.505.954.427.700.122]
        
        Antidepressive Agents, Second-Generation [D27.505.954.427.700.122.050]
        
        Antidepressive Agents, Tricyclic [D27.505.954.427.700.122.055]
        
        Hallucinogens [D27.505.954.427.700.372]
        
        Tranquilizing Agents [D27.505.954.427.700.872]

Antidepressive Agents Preferred

Concept UI: M0001384
Registry Numbers: 0
Scope Note: Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Terms: Antidepressive Agents Preferred Term
Term UI T002759
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1966); Antidepressant Drug
Term UI T000997542
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Antidepressant Medication
Term UI T001095465
Date01/22/2021
LexicalTag NON
ThesaurusID NLM (2022); Antidepressant
Term UI T000996168
Date11/13/2019
LexicalTag NON
ThesaurusID NLM (2021); Antidepressant Drugs
Term UI T002760
Date04/04/1994
LexicalTag NON
ThesaurusID NLM (1995); Antidepressants
Term UI T002758
Date05/04/1987
LexicalTag NON
ThesaurusID UNK (19XX); Antidepressive Agent
Term UI T000997543
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021)

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Antidepressive Agents MeSH Descriptor Data 2025