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Bortezomib
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Bortezomib
Tree Number(s)
D01.029.260.110.500
D01.132.285.500
D02.203.200.500
D03.383.679.450
Unique ID
D000069286
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000069286
Scope Note
A pyrazine and boronic acid derivative that functions as a reversible
PROTEASOME INHIBITOR
. It is used as an
ANTINEOPLASTIC AGENT
in the treatment of
MULTIPLE MYELOMA
and
MANTLE CELL LYMPHOMA
.
Entry Term(s)
LDP-341
PS 341
PS-341
Velcade
Pharm Action
Antineoplastic Agents
Related Numbers
179324-69-7
Public MeSH Note
2016; BORTEZOMIB was indexed under BORONIC ACIDS and PYRAZINES 2000-2015
History Note
2016 (2000)
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2016/05/27
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analogs & derivatives (AA)
analysis (AN)
antagonists & inhibitors (AI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Inorganic Chemicals [D01]
Acids [D01.029]
Acids, Noncarboxylic [D01.029.260]
Boronic Acids [D01.029.260.110]
Bortezomib [D01.029.260.110.500]
Inorganic Chemicals [D01]
Boron Compounds [D01.132]
Boronic Acids [D01.132.285]
Bortezomib [D01.132.285.500]
Organic Chemicals [D02]
Boron Compounds [D02.203]
Boronic Acids [D02.203.200]
Bortezomib [D02.203.200.500]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyrazines [D03.383.679]
Amiloride [D03.383.679.149]
Bortezomib [D03.383.679.450]
Eszopiclone [D03.383.679.600]
Pyrazinamide [D03.383.679.750]
Sitagliptin Phosphate [D03.383.679.875]
Expand All
Collapse All
Bortezomib
Preferred
Concept UI
M0350110
Related Numbers
179324-69-7
Scope Note
A pyrazine and boronic acid derivative that functions as a reversible
PROTEASOME INHIBITOR
. It is used as an
ANTINEOPLASTIC AGENT
in the treatment of
MULTIPLE MYELOMA
and
MANTLE CELL LYMPHOMA
.
Terms
Bortezomib
Preferred Term
Term UI
T000879328
Date
05/06/2015
LexicalTag
NON
ThesaurusID
PS 341
Narrower
Concept UI
M0446631
Terms
PS 341
Preferred Term
Term UI
T400169
Date
11/17/1999
LexicalTag
LAB
ThesaurusID
NLM (1999)
PS-341
Term UI
T543230
Date
06/14/2003
LexicalTag
LAB
ThesaurusID
NLM (2003)
Velcade
Narrower
Concept UI
M0446632
Terms
Velcade
Preferred Term
Term UI
T534905
Date
03/10/2003
LexicalTag
TRD
ThesaurusID
NLM (2003)
LDP-341
Narrower
Concept UI
M0560884
Terms
LDP-341
Preferred Term
Term UI
T796689
Date
09/09/2011
LexicalTag
LAB
ThesaurusID
NLM (2011)
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