MeSH Browser

MeSH Heading: Sitagliptin Phosphate
Tree Number(s): D03.383.129.799.725; D03.383.679.875
Unique ID: D000068900
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000068900
Scope Note: A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.
Entry Term(s): 4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine; Januvia; MK 0431; MK-0431; MK0431; Sitagliptin; Sitagliptin Monophosphate Monohydrate; Sitagliptin Phosphate Anhydrous; Sitagliptin Phosphate Monohydrate
Pharm Action: Hypoglycemic Agents
Incretins
Dipeptidyl-Peptidase IV Inhibitors
Related Numbers: 486460-32-6; 494P4635I6; 654671-77-9; QFP0P1DV7Z
See Also: Linagliptin
Public MeSH Note: 2016; SITAGLIPTIN PHOSPHATE was indexed under PYRAZINES and TRIAZOLES 2005-2015
History Note: 2016 (2005)
Date Established: 2016/01/01
Date of Entry: 2015/07/09
Revision Date: 2016/05/31

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therapeutic use (TU)

toxicity (TO)

urine (UR)

Sitagliptin Phosphate MeSH Descriptor Data 2025