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Maraviroc MeSH Descriptor Data 2021


MeSH Heading
Maraviroc
Tree Number(s)
D02.455.426.392.368.367.726
D03.383.129.799.682
Unique ID
D000077592
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077592
Scope Note
A cyclohexane and triazole derivative that acts as an antagonist of the CCR5 RECEPTOR. It prevents infection by HIV-1 virus strains which use CCR5 as a co-receptor for membrane fusion and cellular entry.
Entry Term(s)
4,4-Difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide
Selzentry
UK-427,857
UK-427857
Pharm Action
HIV Fusion Inhibitors
CCR5 Receptor Antagonists
Registry Number
MD6P741W8A
CAS Type 1 Name
Cyclohexanecarboxamide, 4,4-difluoro-N-((1S)-3-((3-exo)-3-(3-methyl-5-(1-methylethyl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)-
Public MeSH Note
2019; MARAVIROC was indexed under CYCLOHEXANES and TRIAZOLES 2005-2018
History Note
2019 (2005)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
Maraviroc Preferred
Selzentry Narrower
UK-427,857 Narrower
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