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Ketamine MeSH Descriptor Data 2025


MeSH Heading
Ketamine
Tree Number(s)
D02.455.426.392.368.367.652
Unique ID
D007649
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007649
Scope Note
A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.
Entry Term(s)
2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
CI-581
Calipsol
Calypsol
Kalipsol
Ketalar
Ketamine Hydrochloride
Ketanest
Ketaset
Pharm Action
Analgesics
Anesthetics, Dissociative
Excitatory Amino Acid Antagonists
Related Numbers
1867-66-9
6740-88-1
O18YUO0I83
CAS Type 1 Name
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)-
NLM Classification #
QV 81
Previous Indexing
Analgesics (1966-1971)
Anesthetics (1972)
Cyclohexanes (1968-1972)
Public MeSH Note
73
Online Note
use KETAMINE to search CI-581 1969-72 (as Prov)
History Note
73; was CI-581 1969-72 (Prov)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2013/07/08
Ketamine Preferred
Ketalar Narrower
CI-581 Narrower
Ketanest Narrower
Ketamine Hydrochloride Narrower
Calipsol Narrower
Ketaset Narrower
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