MeSH Browser

MeSH Heading: Itraconazole
Tree Number(s): D03.383.129.799.550; D03.383.606.530
Unique ID: D017964
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017964
Scope Note: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
Entry Term(s): Orungal; R-51211; Sporanox
Pharm Action: Antifungal Agents
14-alpha Demethylase Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Related Numbers: 84625-61-6
CAS Type 1 Name: 3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-
Previous Indexing: Ketoconazole/analogs & derivatives (1984-1993)
Public MeSH Note: 94; ITRACONAZOLE was indexed under KETOCONAZOLE/*analogs & derivatives 1984-93
Online Note: use ITRACONAZOLE (NM) to search ITRACONAZOLE 1984-93
History Note: 94; was ITRACONAZOLE (NM) 1984-93
Date Established: 1994/01/01
Date of Entry: 1993/06/04
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Itraconazole MeSH Descriptor Data 2025