NLM Logo

Flunarizine MeSH Descriptor Data 2022


MeSH Heading
Flunarizine
Tree Number(s)
D03.383.606.450
Unique ID
D005444
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D005444
Scope Note
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Entry Term(s)
Flunarizin
Flunarizine Dihydrochloride
Flunarizine Hydrochloride
R-14950
Sibelium
Pharm Action
Anticonvulsants
Calcium Channel Blockers
Histamine H1 Antagonists
Vasodilator Agents
Registry Number
R7PLA2DM0J
Related Numbers
30484-77-6
52468-60-7
C11102TO53
CAS Type 1 Name
Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-, (E)-
NLM Classification #
QV 151
Previous Indexing
Cinnarizine/analogs & derivatives (1975-1986)
Piperazines (1966-1974)
Public MeSH Note
87
History Note
87
Date Established
1987/01/01
Date of Entry
1986/06/16
Revision Date
2016/05/31
Flunarizine Preferred
Sibelium Narrower
Flunarizine Hydrochloride Narrower
R-14950 Narrower
page delivered in 0.175s