MeSH Browser

MeSH Heading: Aripiprazole
Tree Number(s): D03.383.606.170; D03.633.100.810.835.122
Unique ID: D000068180
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000068180
Scope Note: A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.
Entry Term(s): 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone; Abilify; Aripiprazol; OPC 14597; OPC-14597
Pharm Action: Antidepressive Agents
Antipsychotic Agents
Dopamine Agonists
Serotonin 5-HT1 Receptor Agonists
Serotonin 5-HT2 Receptor Antagonists
Dopamine D2 Receptor Antagonists
Registry Number: 82VFR53I78
Public MeSH Note: 2016; ARIPIPRAZOLE was indexed under QUINOLONES 1995-2015 and under PIPERAZINES 1995-2015
History Note: 2016 (1995)
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2018/06/20

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M000602020
Registry Number: 82VFR53I78
Scope Note: A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.
Terms: Aripiprazole Preferred Term
Term UI T000874649
Date02/03/2015
LexicalTag NON
ThesaurusID NLM (2016); 7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone
Term UI T279364
LexicalTag NON
ThesaurusID NLM (1995); Aripiprazol
Term UI T000874920
Date02/09/2015
LexicalTag NON
ThesaurusID NLM (2016)

Aripiprazole MeSH Descriptor Data 2023