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Aripiprazole MeSH Descriptor Data 2021


MeSH Heading
Aripiprazole
Tree Number(s)
D03.383.606.170
D03.633.100.810.835.122
Unique ID
D000068180
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000068180
Scope Note
A piperazine and quinolone derivative that is used primarily as an antipsychotic agent. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A. It is used for the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER, and as an adjunct therapy for the treatment of depression.
Entry Term(s)
7-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyloxy)-3,4-dihydro-2(1H)-quinolinone
Abilify
Aripiprazol
OPC 14597
OPC-14597
Pharm Action
Antidepressive Agents
Antipsychotic Agents
Dopamine Agonists
Serotonin 5-HT1 Receptor Agonists
Serotonin 5-HT2 Receptor Antagonists
Dopamine D2 Receptor Antagonists
Registry Number
82VFR53I78
Public MeSH Note
2016; ARIPIPRAZOLE was indexed under QUINOLONES 1995-2015 and under PIPERAZINES 1995-2015
History Note
2016 (1995)
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2018/06/20
Aripiprazole Preferred
Abilify Narrower
OPC 14597 Narrower
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