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Receptor, Serotonin, 5-HT1A MeSH Descriptor Data 2026


MeSH Heading
Receptor, Serotonin, 5-HT1A
Tree Number(s)
D12.776.543.750.670.800.100.100
D12.776.543.750.695.800.100.100
D12.776.543.750.720.850.100.100
Unique ID
D044282
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D044282
Scope Note
A serotonin receptor subtype found distributed through the CENTRAL NERVOUS SYSTEM where they are involved in neuroendocrine regulation of ACTH secretion. The fact that this serotonin receptor subtype is particularly sensitive to SEROTONIN RECEPTOR AGONISTS such as BUSPIRONE suggests its role in the modulation of ANXIETY and DEPRESSION.
Entry Version
RECEPT SEROTONIN 5 HT1A
Entry Term(s)
5-HT(1A) Receptor
5-HT1A Receptor
5-Hydroxytryptamine 1A Receptor
5-Hydroxytryptamine 1A Receptors
Receptor, 5-Hydroxytryptamine 1A
Serotonin 1A Receptor
Serotonin Receptor, 5-HT1A
Serotonin, 5-HT1a Receptor
Registry Numbers
112692-38-3
Previous Indexing
Receptors, Serotonin (1993-2003)
Public MeSH Note
2004; RECEPTOR, SEROTONIN 1A (now RECEPTOR, SEROTONIN, 5-HT1A) was indexed under RECEPTORS, SEROTONIN 1993-2003
History Note
2004; use RECEPTOR SEROTONIN 5 HT1 SUBCLASS (NM) 1993-2003
Entry Combination
agonists:Serotonin 5-HT1 Receptor Agonists
antagonists & inhibitors:Serotonin 5-HT1 Receptor Antagonists
Date Introduced
2004/01/01
Last Updated
2016/07/01
Receptor, Serotonin, 5-HT1A Preferred
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