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Receptor, Serotonin, 5-HT1B MeSH Descriptor Data 2026
A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.
Entry Version
RECEPT SEROTONIN 5 HT1B
Entry Term(s)
5-HT(1B) Receptor
5-HT(1Dbeta) Receptor
5-HT1B Receptor
5-HT1Dbeta Receptor
5-Hydroxytryptamine 1B Receptor
5-Hydroxytryptamine 1B Receptors
Receptor, 5-Hydroxytryptamine 1B
Receptor, Serotonin Type 1Dbeta
Serotonin 1B Receptor
Serotonin 1D Beta Receptor
Serotonin 1Dbeta Receptor
Serotonin 1Dbeta Receptors
Registry Numbers
0
Previous Indexing
Receptors, Serotonin (1993-2003)
Public MeSH Note
2004; SEROTONIN 1B RECEPTOR (now RECEPTOR, SEROTONIN, 5-HT1B) was indexed under RECEPTORS, SEROTONIN 1993-2003; SEROTONIN 1D BETA RECEPTOR (now RECEPTOR, SEROTONIN, 5-HT1B) was indexed under RECEPTORS, SEROTONIN 1995-2003
History Note
2004; use RECEPTOR, SEROTONIN, 5-HT1B (NM) 1993-2003
A serotonin receptor subtype found at high levels in the BASAL GANGLIA and the frontal cortex. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1D RECEPTOR. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigraine effect.