MeSH Browser

MeSH Heading: Antipsychotic Agents
Tree Number(s): D27.505.696.277.950.040; D27.505.954.427.210.950.040; D27.505.954.427.700.872.331
Unique ID: D014150
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D014150
Annotation: note entry term ANTIPSYCHOTIC EFFECT: use only for the antipsychotic effect of a chemical substance
Scope Note: Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Entry Term(s): Antipsychotic; Antipsychotic Agent; Antipsychotic Drug; Antipsychotic Drugs; Antipsychotic Effect; Antipsychotic Effects; Antipsychotic Medication; Antipsychotics; Major Tranquilizer; Major Tranquilizers; Neuroleptic; Neuroleptic Agent; Neuroleptic Agents; Neuroleptic Drug; Neuroleptic Drugs; Neuroleptics; Tranquilizing Agents, Major; Tranquillizing Agents, Major
Registry Numbers: 0
NLM Classification #: QV 77.9
Previous Indexing: Tranquilizing Agents (1966-1974)
See Also: Dopamine Antagonists
Public MeSH Note: 95; was TRANQUILIZING AGENTS, MAJOR 1975-94; ANTIPSYCHOTIC AGENTS was see TRANQUILIZING AGENTS, MAJOR 1975-94; NEUROLEPTICS was see TRANQUILIZING AGENTS 1975-78, was see under TRANQUILIZING AGENTS 1969-74
Online Note: use ANTIPSYCHOTIC AGENTS to search TRANQUILIZING AGENTS, MAJOR 1975-94; use TRANQUILIZING AGENTS to search NEUROLEPTICS 1969-94
History Note: 95; was TRANQUILIZING AGENTS, MAJOR 1975-94; ANTIPSYCHOTIC AGENTS was see TRANQUILIZING AGENTS, MAJOR 1975-94; NEUROLEPTICS was see TRANQUILIZING AGENTS 1975-78, was see under TRANQUILIZING AGENTS 1969-74
Date Established: 1975/09/01
Date of Entry: 1999/01/01
Revision Date: 2021/03/12

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Physiological Effects of Drugs [D27.505.696]
    - Central Nervous System Depressants [D27.505.696.277]
      - Tranquilizing Agents [D27.505.696.277.950]
        
        Anti-Anxiety Agents [D27.505.696.277.950.015]
        
        Antimanic Agents [D27.505.696.277.950.025]
        
        Antipsychotic Agents [D27.505.696.277.950.040]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Central Nervous System Agents [D27.505.954.427]
      - Central Nervous System Depressants [D27.505.954.427.210]
        
        Tranquilizing Agents [D27.505.954.427.210.950]
        
        Anti-Anxiety Agents [D27.505.954.427.210.950.015]
        
        Antimanic Agents [D27.505.954.427.210.950.025]
        
        Antipsychotic Agents [D27.505.954.427.210.950.040]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Therapeutic Uses [D27.505.954]
    - Central Nervous System Agents [D27.505.954.427]
      - Psychotropic Drugs [D27.505.954.427.700]
        
        Tranquilizing Agents [D27.505.954.427.700.872]
        
        Anti-Anxiety Agents [D27.505.954.427.700.872.015]
        
        Antimanic Agents [D27.505.954.427.700.872.025]
        
        Antipsychotic Agents [D27.505.954.427.700.872.331]

Antipsychotic Agents Preferred

Concept UI: M0021770
Registry Numbers: 0
Scope Note: Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Terms: Antipsychotic Agents Preferred Term
Term UI T041437
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Tranquilizing Agents, Major
Term UI T041439
Date01/26/1994
LexicalTag NON
ThesaurusID NLM (1995); Tranquillizing Agents, Major
Term UI T041440
Date12/14/1978
LexicalTag NON
ThesaurusID UNK (19XX); Major Tranquilizer
Term UI T000998061
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Antipsychotic Drug
Term UI T000996736
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Antipsychotic Agent
Term UI T000996737
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Antipsychotic Medication
Term UI T001095466
Date01/22/2021
LexicalTag NON
ThesaurusID NLM (2022); Neuroleptic Agent
Term UI T000996738
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Neuroleptic Drug
Term UI T000996739
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Neuroleptic
Term UI T000996740
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Antipsychotic
Term UI T000996207
Date11/14/2019
LexicalTag NON
ThesaurusID NLM (2021); Antipsychotic Drugs
Term UI T041443
Date04/04/1994
LexicalTag NON
ThesaurusID NLM (1995); Antipsychotics
Term UI T041442
Date01/26/1994
LexicalTag NON
ThesaurusID NLM (1995); Major Tranquilizers
Term UI T041445
Date04/04/1994
LexicalTag NON
ThesaurusID NLM (1995); Neuroleptic Agents
Term UI T041441
Date04/04/1994
LexicalTag NON
ThesaurusID NLM (1995); Neuroleptic Drugs
Term UI T041444
Date04/04/1994
LexicalTag NON
ThesaurusID NLM (1995); Neuroleptics
Term UI T041438
Date11/25/1977
LexicalTag NON
ThesaurusID UNK (19XX)

Antipsychotic Effect Related

Antipsychotic Agents MeSH Descriptor Data 2025