MeSH Browser

MeSH Heading: Signaling Lymphocytic Activation Molecule Family Member 1
Tree Number(s): D09.400.430.890.736.500; D12.776.395.550.736.500; D12.776.543.550.746.500; D12.776.543.750.705.970.500
Unique ID: D000071177
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071177
Scope Note: A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
Entry Term(s): CD150 Antigen; CDw150 Protein; SLAM Protein; SLAM Receptor; SLAMF1 Protein; SLAMF1 Receptor
Public MeSH Note: 2017; SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE FAMILY MEMBER 1 was indexed under RECEPTORS, CELL SURFACE and ANTIGENS, CD 2007-2016; and under GLYCOPROTEINS and IMMUNOGLOBULINS 1995-2006
History Note: 2017 (1995)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0249384
Scope Note: A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
Terms: Signaling Lymphocytic Activation Molecule Family Member 1 Preferred Term
Term UI T000893273
Date01/07/2016
LexicalTag NON
ThesaurusID NLM (2011); CDw150 Protein
Term UI T000893275
Date01/07/2016
LexicalTag NON
ThesaurusID NLM (1995); SLAM Protein
Term UI T000893276
Date01/07/2016
LexicalTag ABX
ThesaurusID NLM (1995); SLAMF1 Protein
Term UI T000893278
Date01/07/2016
LexicalTag ABX
ThesaurusID NLM (2017); SLAM Receptor
Term UI T000893279
Date01/07/2016
LexicalTag ABX
ThesaurusID NLM (2017); SLAMF1 Receptor
Term UI T000893280
Date01/07/2016
LexicalTag ABX
ThesaurusID NLM (2017); CD150 Antigen
Term UI T000893281
Date01/07/2016
LexicalTag NON
ThesaurusID NLM (2001)

Signaling Lymphocytic Activation Molecule Family Member 1 MeSH Descriptor Data 2025