Toggle navigation
Search
Tree View
MeSH on Demand
MeSH 2025
About
Suggestions
Contact Us
Fibrillin-1
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Fibrillin-1
Tree Number(s)
D09.400.430.800.500
D12.776.395.341.500
D12.776.860.300.400.500
Unique ID
D000071838
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071838
Scope Note
A fibrillin (FBN1) that functions as a structural support protein for
MICROFIBRILS
. It also regulates the maturation of
OSTEOBLASTS
by controlling the availability and concentration of
TGF-BETA
and
BONE MORPHOGENETIC PROTEINS
. Mutations in the FBN1 gene are associated with
MARFAN SYNDROME
.
Entry Term(s)
Profibrillin 1
Profibrillin-1
Registry Numbers
0
Public MeSH Note
2017; see FIBRILLIN 1985-2016
History Note
2017; use FIBRILLIN 1985-2016
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2023/03/16
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
drug effects (DE)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
ultrastructure (UL)
urine (UR)
Carbohydrates [D09]
Glycoconjugates [D09.400]
Glycoproteins [D09.400.430]
Fibrillins [D09.400.430.800]
Fibrillin-1 [D09.400.430.800.500]
Fibrillin-2 [D09.400.430.800.750]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Fibrillins [D12.776.395.341]
Fibrillin-1 [D12.776.395.341.500]
Fibrillin-2 [D12.776.395.341.750]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Scleroproteins [D12.776.860]
Extracellular Matrix Proteins [D12.776.860.300]
Fibrillins [D12.776.860.300.400]
Fibrillin-1 [D12.776.860.300.400.500]
Fibrillin-2 [D12.776.860.300.400.750]
Expand All
Collapse All
Fibrillin-1
Preferred
Concept UI
M0132396
Registry Numbers
0
Scope Note
A fibrillin (FBN1) that functions as a structural support protein for
MICROFIBRILS
. It also regulates the maturation of
OSTEOBLASTS
by controlling the availability and concentration of
TGF-BETA
and
BONE MORPHOGENETIC PROTEINS
. Mutations in the FBN1 gene are associated with
MARFAN SYNDROME
.
Terms
Fibrillin-1
Preferred Term
Term UI
T000896837
Date
03/09/2016
LexicalTag
NON
ThesaurusID
NLM (1985)
Profibrillin 1
Narrower
Concept UI
M0246918
Registry Numbers
0
Terms
Profibrillin 1
Preferred Term
Term UI
T000896839
Date
03/09/2016
LexicalTag
NON
ThesaurusID
NLM (1985)
Profibrillin-1
Term UI
T000896840
Date
03/09/2016
LexicalTag
NON
ThesaurusID
NLM (1985)
page delivered in 0.157s