MeSH Browser

MeSH Heading: Acedapsone
Tree Number(s): D02.886.590.263.050
Unique ID: D000072
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072
Scope Note: Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.
Entry Term(s): 4',4'''-Sulfonylbis(acetanilide); 4,4'-Diacetyldiaminodiphenylsulfone; Acetyldiphenazonum; DADDS; Diacetyldapsone; Hansolar; Rodilone; Sulfadiamine
Pharm Action: Anti-Infective Agents
Antimalarials
Leprostatic Agents
Related Numbers: 77-46-3
CAS Type 1 Name: Acetamide, N,N'-(sulfonyldi-4,1-phenylene)bis-
Previous Indexing: Acetamides (1975); Acetanilides (1972-1974); Dapsone/analogs & derivatives (1975); Sulfones (1972-1974)
Public MeSH Note: 91; was see under DAPSONE 1976-90
History Note: 91(76); was see under DAPSONE 1976-90
Date Established: 1991/01/01
Date of Entry: 1975/07/25
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0000103
Related Numbers: 77-46-3
Scope Note: Acetylated sulfone that is slowly metabolized to give long-term, low blood levels of DAPSONE. It has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.
Terms: Acedapsone Preferred Term
Term UI T000183
Date01/01/1999
LexicalTag NON
ThesaurusID; 4',4'''-Sulfonylbis(acetanilide)
Term UI T000181
Date08/13/1980
LexicalTag NON
ThesaurusID; 4,4'-Diacetyldiaminodiphenylsulfone
Term UI T000182
Date08/13/1980
LexicalTag NON
ThesaurusID UNK (19XX); Acetyldiphenazonum
Term UI T000184
Date07/25/1975
LexicalTag NON
ThesaurusID UNK (19XX); DADDS
Term UI T000185
Date07/25/1975
LexicalTag ABB
ThesaurusID; Diacetyldapsone
Term UI T000186
Date07/25/1975
LexicalTag NON
ThesaurusID; Sulfadiamine
Term UI T000189
Date01/24/1990
LexicalTag NON
ThesaurusID

Acedapsone MeSH Descriptor Data 2025