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Dapsone MeSH Descriptor Data 2021


MeSH Heading
Dapsone
Tree Number(s)
D02.886.590.263
Unique ID
D003622
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003622
Scope Note
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
Entry Term(s)
4,4'-Diaminophenyl Sulfone
Avlosulfone
DADPS
Dapsoderm-X
Dapson-Fatol
Diaminodiphenylsulfone
Diaphenylsulfone
Disulone
Sulfona
Sulfonyldianiline
Pharm Action
Anti-Infective Agents
Antimalarials
Folic Acid Antagonists
Leprostatic Agents
Registry Number
8W5C518302
Related Numbers
80-08-0
NLM Classification #
QV 259
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/05
Dapsone Preferred
Sulfona Narrower
Dapson-Fatol Narrower
Disulone Narrower
Avlosulfone Narrower
Dapsoderm-X Narrower
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