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ERG1 Potassium Channel MeSH Descriptor Data 2023


MeSH Heading
ERG1 Potassium Channel
Tree Number(s)
D12.776.157.530.400.600.900.249.500
D12.776.543.550.450.750.900.249.500
D12.776.543.585.400.750.900.249.500
Unique ID
D000072237
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072237
Scope Note
One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
Entry Term(s)
Ether-A-Go-Go-Related Potassium Channel 1
Kv11.1 Protein-Potassium Channel
Potassium Voltage-Gated Channel, Subfamily H, Member 2
Registry Number
0
Public MeSH Note
2017; ERG1 POTASSIUM CHANNEL was indexed under POTASSIUM CHANNELS, VOLTAGE-GATED 2005-2008, and under ETHER-A-GO-GO POTASSIUM CHANNELS 2009-2016
History Note
2017 (2001)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/07/05
ERG1 Potassium Channel Preferred
Kv11.1 Protein-Potassium Channel Narrower
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