- Concept UI
- M0386712
- Registry Numbers
- 0
- Scope Note
- One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA.
- Terms
-
ERG1 Potassium Channel
Preferred Term
Term UI
T000898754
Date04/11/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
-
Ether-A-Go-Go-Related Potassium Channel 1
Term UI
T000899409
Date04/21/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
-
Potassium Voltage-Gated Channel, Subfamily H, Member 2
Term UI
T000899410
Date04/21/2016
LexicalTag
NON
ThesaurusID
NLM (2017)