MeSH Browser

MeSH Heading: Saporins
Tree Number(s): D08.811.277.450.430.700.500.500; D12.776.765.710.500.250
Unique ID: D000076985
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000076985
Scope Note: Type 1 ribosome-inactivating proteins derived from SAPONARIA OFFICINALIS that function through endohydrolysis of the N-glycosidic bond at single ADENOSINE residues of 28S RIBOSOMAL RNA. They are used as IMMUNOTOXINS.
Entry Term(s): RIP Ribosome-Inactivating Protein; Ribosome-Inactivating Protein; SAP5 Protein; SAP6 Protein; Saporin; Saporin 5 Protein; Saporin 6 Protein; Saporin Protein; Saporin-S9 Protein
Registry Numbers: EC 3.2.2.22; 0
See Also: Saponins
Public MeSH Note: 2019; see SAPORIN 1985-2018
History Note: 2019 (1985)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2021/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000638939
Registry Numbers: EC 3.2.2.22
Scope Note: Type 1 ribosome-inactivating proteins derived from SAPONARIA OFFICINALIS that function through endohydrolysis of the N-glycosidic bond at single ADENOSINE residues of 28S RIBOSOMAL RNA. They are used as IMMUNOTOXINS.
Terms: Saporins Preferred Term
Term UI T000935923
Date11/14/2017
LexicalTag NON
ThesaurusID NLM (2019); RIP Ribosome-Inactivating Protein
Term UI T001105244
Date04/26/2021
LexicalTag ACX
ThesaurusID NLM (2022); Saporin
Term UI T000935928
Date11/14/2017
LexicalTag NON
ThesaurusID NLM (2008); Ribosome-Inactivating Protein
Term UI T000938276
Date12/27/2017
LexicalTag NON
ThesaurusID NLM (2019); Saporin Protein
Term UI T000938277
Date12/27/2017
LexicalTag NON
ThesaurusID NLM (2019)

Saporins MeSH Descriptor Data 2025