MeSH Browser

MeSH Heading: Temozolomide
Tree Number(s): D02.925.200.500; D03.383.129.308.240.500
Unique ID: D000077204
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077204
Scope Note: A dacarbazine derivative that is used as an alkylating antineoplastic agent for the treatment of MALIGNANT GLIOMA and MALIGNANT MELANOMA.
Entry Term(s): 8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one; CCRG 81045; CCRG-81045; M&B 39831; M&B-39831; Methazolastone; NSC 362856; NSC-362856; TMZ-Bioshuttle; TMZA-HE; Temodal; Temodar; Temozolomide Hexyl Ester
Pharm Action: Antineoplastic Agents, Alkylating
Registry Numbers: YF1K15M17Y; 0
Related Numbers: 85622-93-1
Public MeSH Note: 2019; TEMOZOLOMIDE was indexed under DACARBAZINE 1989-2019, and under IMIDAZOLES 1985-1988
History Note: 2019 (1985)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/01/11

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Temozolomide MeSH Descriptor Data 2025