MeSH Browser

MeSH Heading: Dacarbazine
Tree Number(s): D02.925.200; D03.383.129.308.240
Unique ID: D003606
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003606
Scope Note: An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)
Entry Term(s): 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide; Biocarbazine; DIC; DTIC; DTIC-Dome; Decarbazine; Deticene; Dimethyl Imidazole Carboxamide; Dimethyl Triazeno Imidazole Carboxamide; ICDT; NSC-45388
Pharm Action: Antineoplastic Agents, Alkylating
Related Numbers: 4342-03-4
CAS Type 1 Name: 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-
Previous Indexing: Amides (1966-1974); Azo Compounds (1966-1972); Imidazoles (1966-1974); Triazenes (1972-1974)
Public MeSH Note: 80; see TRIAZENES 1975-79
History Note: 80(75)
Date Established: 1980/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/05/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0005636
Related Numbers: 4342-03-4
Scope Note: An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564)
Terms: Dacarbazine Preferred Term
Term UI T010494
Date01/01/1999
LexicalTag NON
ThesaurusID; DIC
Term UI T010496
Date07/31/1980
LexicalTag ABB
ThesaurusID UNK (19XX); Dimethyl Imidazole Carboxamide
Term UI T010497
Date03/05/1981
LexicalTag NON
ThesaurusID UNK (19XX); Dimethyl Triazeno Imidazole Carboxamide
Term UI T010498
Date09/15/1983
LexicalTag NON
ThesaurusID UNK (19XX); ICDT
Term UI T010499
Date06/08/1981
LexicalTag NON
ThesaurusID UNK (19XX); Decarbazine
Term UI T010501
Date06/08/1981
LexicalTag NON
ThesaurusID UNK (19XX); 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
Term UI T010502
Date04/06/1995
LexicalTag NON
ThesaurusID; DTIC
Term UI T010503
Date11/11/1974
LexicalTag NON
ThesaurusID

Dacarbazine MeSH Descriptor Data 2025