MeSH Browser

MeSH Heading: Levamisole
Tree Number(s): D02.886.675.346; D03.383.129.308.480; D03.383.129.708.346
Unique ID: D007978
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D007978
Scope Note: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
Entry Term(s): Decaris; Dekaris; L-Tetramisole; Levamisole Hydrochloride; Levotetramisole; Solaskil
Pharm Action: Adjuvants, Immunologic
Antinematodal Agents
Antirheumatic Agents
Related Numbers: 14769-73-4; 16595-80-5; DL9055K809
CAS Type 1 Name: Imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, (S)-
Public MeSH Note: 74
History Note: 74
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0012431
Related Numbers: 14769-73-4; 16595-80-5; DL9055K809
Scope Note: An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
Terms: Levamisole Preferred Term
Term UI T023774
Date01/01/1999
LexicalTag NON
ThesaurusID; Levotetramisole
Term UI T023773
Date05/15/1976
LexicalTag NON
ThesaurusID UNK (19XX); L-Tetramisole
Term UI T023775
Date05/15/1976
LexicalTag NON
ThesaurusID UNK (19XX)

Levamisole MeSH Descriptor Data 2025