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Chlormethiazole MeSH Descriptor Data 2021


MeSH Heading
Chlormethiazole
Tree Number(s)
D02.886.675.180
D03.383.129.708.180
Unique ID
D002719
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002719
Scope Note
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors.
Entry Term(s)
Clomethiazole
Distraneurin
Pharm Action
Anticonvulsants
Hypnotics and Sedatives
Neuroprotective Agents
GABA Modulators
Registry Number
0C5DBZ19HV
Related Numbers
533-45-9
CAS Type 1 Name
Thiazole, 5-(2-chloroethyl)-4-methyl-
Previous Indexing
Hypnotics and Sedatives (1966-1967)
Thiazoles (1966-1967)
Public MeSH Note
68; CHLORETHIAZOLE was see CHLORMETHAZOLE 1975-95
History Note
68; CHLORETHIAZOLE was see CHLORMETHAZOLE 1975-95
Date Established
1968/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/28
Chlormethiazole Preferred
Distraneurin Narrower
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