MeSH Browser

MeSH Heading: Ondansetron
Tree Number(s): D03.383.129.308.690; D03.633.100.473.144.500; D03.633.300.148.500
Unique ID: D017294
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017294
Scope Note: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Entry Term(s): 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-; GR-38032F; GR38032F; Ondansetron Hydrochloride; Ondansetron Monohydrochloride; Ondansetron Monohydrochloride Dihydrate; Ondansetron, (+,-)-Isomer; Ondansetron, (R)-Isomer; Ondansetron, (S)-Isomer; SN-307; Zofran; Zofran ODT
Pharm Action: Antiemetics
Antipruritics
Serotonin 5-HT3 Receptor Antagonists
Registry Number: 4AF302ESOS
Related Numbers: 110707-92-1; 99614-01-4; 99614-02-5; 99614-58-1; 99614-60-5; NMH84OZK2B
Previous Indexing: Imidazoles (1987-1992)
Public MeSH Note: 93; ONDANSETRON was indexed under IMIDAZOLES 1987-92
Online Note: use ONDANSETRON (NM) to search ONDANSETRON 1987-92
History Note: 93; was ONDANSETRON (NM) 1987-92
Date Established: 1993/01/01
Date of Entry: 1992/05/19
Revision Date: 2022/07/14

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0026254
Registry Number: 4AF302ESOS
Related Numbers: 110707-92-1; 99614-01-4; 99614-02-5; 99614-58-1; 99614-60-5; NMH84OZK2B
Scope Note: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Terms: Ondansetron Preferred Term
Term UI T051619
Date01/01/1999
LexicalTag NON
ThesaurusID; Ondansetron, (+,-)-Isomer
Term UI T359455
Date09/13/1999
LexicalTag NON
ThesaurusID NLM (1999); 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-
Term UI T000951099
Date02/01/2019
LexicalTag NON
ThesaurusID NLM (2020)

Ondansetron MeSH Descriptor Data 2023