MeSH Browser

MeSH Heading: Topiramate
Tree Number(s): D09.947.875.359.250.500; D09.947.875.465.354.500
Unique ID: D000077236
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077236
Scope Note: A sulfamate-substituted fructose analog that was originally identified as a hypoglycemic agent. It is used for the treatment of EPILEPSY and MIGRAINE DISORDERS, and may also promote weight loss.
Entry Term(s): 2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate; Epitomax; McN 4853; McN-4853; Topamax; USL255
Pharm Action: Anticonvulsants
Hypoglycemic Agents
Related Numbers: 97240-79-4
Public MeSH Note: 2019; TOPIRAMATE was indexed under FRUCTOSE 1987-2018
History Note: 2019 (1987)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/19

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Topiramate MeSH Descriptor Data 2025