MeSH Browser

MeSH Heading: Modafinil
Tree Number(s): D02.455.426.559.389.115.550
Unique ID: D000077408
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077408
Scope Note: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
Entry Term(s): 2-((Diphenylmethyl)sulfinyl)acetamide; 2-((R)-(Diphenylmethyl)sulfinyl)acetamide; 2-(Benzhydrylsulfinyl)acetamide; 2-Benzhydrylsulfinylacetamide; Alertec; Armodafinil; Benzhydrylsulfinylacetamide; CRL 40476; CRL-40476; Modiodal; Nuvigil; Provigil; R-Modafinil; Sparlon
Pharm Action: Central Nervous System Stimulants
Wakefulness-Promoting Agents
Cytochrome P-450 CYP3A Inducers
Related Numbers: 68693-11-8; V63XWA605I
Public MeSH Note: 2019; MODAFINIL was indexed under BENZHYDRYL COMPOUNDS 1986-2018
History Note: 2019 (1986)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2022/05/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0140282
Related Numbers: 68693-11-8; V63XWA605I
Scope Note: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
Terms: Modafinil Preferred Term
Term UI T000939619
Date01/24/2018
LexicalTag NON
ThesaurusID; 2-Benzhydrylsulfinylacetamide
Term UI T001119766
Date04/11/2022
LexicalTag NON
ThesaurusID NLM (2023); 2-((Diphenylmethyl)sulfinyl)acetamide
Term UI T000939620
Date01/24/2018
LexicalTag NON
ThesaurusID NLM (1986); 2-(Benzhydrylsulfinyl)acetamide
Term UI T001119765
Date04/11/2022
LexicalTag NON
ThesaurusID NLM (2023)

Modafinil MeSH Descriptor Data 2025